Study Reinforces Value of Heart Team Approach When Making Treatment Decisions

Specialty Hospital of Central Jersey’s medical staff stays current on the latest research on cardiothoracic surgery.  Here’s one study we found interesting published last month.

Coronary artery bypass grafting (CABG) surgery may be the best treatment option for most patients with more than one blocked heart artery, according to the findings of a research study published the May 2 issue of  The Annals of Thoracic Surgery, published by Elsevier.

“Our data demonstrate a significant mortality benefit with CABG over percutaneous coronary intervention (PCI), and this benefit is consistent across virtually all major patient groups, suggesting that CABG should be considered in broader patient populations, not just in cases of patients with diabetes and left ventricular dysfunction, which is what is commonly practiced,” said lead author Suresh R. Mulukutla, MD, from the University of Pittsburgh Medical Center (UPMC) in Pennsylvania, PA, USA, in a statement announcing the publication of this cardiothoracic surgery procedure.

 Taking a Look at CABG and PCI Patient Outcomes

Dr. Mulukutla and colleagues examined data gleaned from two major clinical outcomes registries for heart patients, specifically the Society of Thoracic Surgeons (STS) National Database, and the American College of Cardiology Foundation National Cardiovascular Data Registry (NCDR). The researchers identified patients with multivessel coronary artery disease who underwent CABG or PCI between 2010 and 2018 at UPMC. Those who met the study’s eligibility criteria were separated into two groups—CABG and PCI—each including 844 patients. The analyses focused on outcomes for mortality, readmission and revascularization.

According to the researchers, the estimated one-year mortality for patients in the CABG group was 7.2 percent, as compared to 11.5 percent the PCI group. The CABG group also experienced lower risk of hospital readmission (28.1 percent vs. 38.4 percent) and revascularization (1.0 percent vs. 6.7 percent) than the PCI group,” they said.

Dr. Mulukutla noted that a point in the study is the “focus on the current era of revascularization with the most currently available stents.”

“This research is really a modern, ‘real-world’ experience. While randomized clinical trials are clearly important, real-world analyses also can be very instructive because they provide insights on how we are making clinical decisions. For instance, the last several years have seen a shift toward more PCI over CABG. While there may be valid reasons for this, our data—which show CABG outperforming PCI in almost every patient group—should push us to further discuss all of the options,” says Mulukutla.

PCI, commonly referred to as angioplasty, is a nonsurgical procedure that uses a thin, flexible catheter placed into an artery in the groin or arm. A balloon on the end of the catheter is positioned in the narrowed coronary artery and slowly inflated to open-up the blockage. A metal mesh tub, called a stent, is left behind to help keep the artery from collapsing. Drugs attached to the stent help prevent the body from reacting to the stent and shutting down the artery again.

Coronary artery bypass grafting, referred to as CABG, the most commonly performed heart operation in the United States, is designed to bypass the blockages in the coronary arteries in order to create a new path for blood flow to the heart. The surgeon removes a healthy blood vessel, usually from the leg, arm, chest, or abdomen, and connects it to the other arteries (usually the aorta) in the heart. This enables blood flow to “bypass” or go around the diseased or blocked portion of the coronary artery.

Choosing the Best Cardiac Procedure Not Always Clear-Cut

According to Dr. Mulukutla, the decision between open heart surgery and PCI for treatment of patients with multiple narrowed arteries is not always clear-cut. Thus, these more complex treatment decisions should be made with the guidance of a heart care team, he says..

“Both cardiac surgery and stenting have roles among patients with coronary artery disease,” said

Dr. Mulukutla. “Because of this, it is important to deliberate carefully with the help of a heart team. The team can ensure that a multidisciplinary approach is used when offering recommendations to patients and assisting them in making informed decisions,” he says.

A heart care team generally includes cardiothoracic surgeons and cardiologists. Other health care providers such as primary care physicians, physician assistants, nurse practitioners, imaging specialists, and anesthesiologists also may be part of the team. This staffing approach leverages the expertise of these advanced practice providers in an effort to improve the efficiency and advance the quality of care for patients.

With revascularization, heart team input to the patient is often limited because PCI can be completed at the time of a patient’s diagnostic procedure. When this happens, the physicians do not have the opportunity to discuss the array of treatment options that can be chosen. As a result, the practical and consistent use of the heart team for decision-making in the treatment of patients with complex coronary artery diseases is lacking, Dr. Mulukutla explained.

“We are working to better facilitate a heart team approach and overcome some of the limitations given the current infrastructure of how these decisions are made,” said Dr. Mulukutla. “We also are continuing to identify specific patient populations that may benefit from either CABG or PCI so that we can best advocate for our patients.” he says.